Description

Transplantation     Aphaeresis     BM laboratory & Out-Patient clinic    Support facilities   Hematology unit

1.Transplant unit

Our goal at the Hematology Unit and the Bone Marrow Transplantation Center is to provide the best class of care for the patients and their family using a team approach. Patients are a vital part of this team. In fact, they are the MOST important team member, and we encourage them to take an active role in the treatment and the recovery. Over the course(s) for the treatment of of the hematological diseases and/or transplant, the patient will be cared for by a large number of staff members. At times this may seem overwhelming.

We are all working to see the patient successfully through his transplant

The transplant unit includes 20 single-room intensive care beds equipped for special needs of HSCT and capable of satisfying the standard criteria for patient isolation:

• 20 vertical laminar airflow cabins with (fig 2):

  • HEPA filters

  • Positive pressure.

  • Air conditioned

  • With its own cooling and heating systems

  • UV sterilization systems for water in each private bathroom.

• Patient’s monitors: for continuous measurement of vital signs especially pulse, BP, and PO2.

• Sterilization appliances: including autoclaves and cold sterilizers used in sterilization of food and instruments or otherwise.

• Blood component irradiator: used for irradiation of blood and platelets prior to their transfusion.

• Visiting room: through which the patient's relatives can be contact with through a closed television circuit.

• Central monitoring unit: Which enables both the medical and nursing staff to monitor patients on 24 hour basis. using closed monitoring circuit

2. Aphaeresis uint : contaning                             Up

• Blood component separaror machines for separation of different blood components especially PBSC,single donor platelets as well as plasma.

• Laminar airflow hood with triple HEPA filters: which is used to ensur maximum hygienic conditions for the manipulation of the stem cells prior to their storage in LN container.

• PBSC cryopreservation system: which include controlled rate freezer,liquid nitrogen (LN) supply tanks and liquid nitrogen storage system for PBCS bage.

• Platelet agitator/incubator for storage of platelets.

• Plasma thawing system: for thawing of stem cells and all blood products.

• Donation chairs.

3. BM Laboratory                                                    Up

• Flow cytometer: Which is used to measure the number of CD34+ cells to be infused to the patient.
• HLA typing: allogeneic BMT is carried out in close cooperation with a recognized laboratory experienced in histocompatiblity testing.

4. Out-patient clinic and post transplant FU                        Up

• The transplant center is attached to an out-patient clinic comprising a Day Care center wher facilities exist for the administrations of chemotherapy, blood product transfusion and bone marrow examiniations.

• It should be possible for a patient to obtain specialist advice by telephone on a 24-hour basis.

• It should alwas be passible to re-admit to the transplant center a patient who develops complications.

5. Support facilitirs                                                               Up

• Operating theartre : the transplant staff utilizing bone marrow chould have access to an operating theatre and associated staff on regular basis.

• Radiation therapy unit: capable of administering fractionated total body irradiation (TBI) with dosimetric controls, Also irradiated blood products should always available after HSCT in order to prevent post-transfusion GVHD.

• Microbiology lab: capable of performing all routine microbiological investigations.

  • including bacterial sensitivities and viral and fungal isolation. Diagnostic tests should by available on a daily basis including weekends.

• Hematology and chemical pathology laboratories: the transplant unit has a ready access to a laboratory providing hematology and chemical pathology services on a 24-hour basis.

• Cytogenetic laboratory

• Histopathology service: Provided by a designated pathologyist experienced in the specific aspects organ toxicities associated with HSCT Specially the histological features of acute and chronic GVHD.

• Radiology and imaging: The necessary X-ray diagnostic facilities are available on a 24-hour basis. The transplant unit has ready access to a fully equipped radiology department with facilities for computed tomography (CT) scanning and magnetic resonance imaging (MRI).

• Blood product support: providing

  • Routine supplies of erythrocytes ,platelets and other blood products.

  • Special blood products: e.g. HLA-matched platelets, filtered or CMV-negative blood (if indicated)

• Consultation with other medical specialties: the unit is integrated into a large Medical center in which all major medical specialties are represented e.g. brochoscopy, endoscopy, and intensive care unit.

• Data collection and reporting: are integral parts of treatment and permit comparisons with results achieved in other hospitals.

The Hematology Unit comprises of eleven air-conditioned doubled bedrooms and six single isolation rooms with private bathroom in each room. All of this contributes towards ensuring a maximum and sterile environment.

• The Pharesis Room:The Pharesis room serves the hematology as the blood component separators are used for collection of single donor platelets as well as plasma pharesis to serve the patients.

The Procedure room is available for minor diagnostic and therapeutic procedures as bone marrow aspiration or bone marrow biopsy, as well as intrathecal chemotherapy.

• Day Care Unit: Serves the Hematology unit to facilitate application one day therapy for the patients